Ukufunyanwa ngokukhawuleza kosulelo lwegazi

Usulelo lwegazi (i-BSI) lubhekisa kwi-sydrome ye-infroomatory syndrome ebangelwa kukuhlaselwa kweentsholongwane ezahlukeneyo ze-pitoorganic kunye neetyhefu zazo kwigazi.

Isifundo sesi sifo sihlala siphawulwa kukusebenza kunye nokukhutshwa kwabalamli abakhuthazayo, kubangela uthotho lweempawu zekliniki ezinje nge-fever enkulu, i-rash, i-rashy kunye nenqanaba elininzi lokubulawa kwabantu. ifunyenwe ha) seppis kunye neemeko zothusayo ze-septic, i-accounting ngama-40% amatyala kunye ne-20% ye-ICU efumana amatyala. Kwaye inxulumene ngokusondeleyo neproginosisis engalunganga, ngakumbi ngaphandle konyango lwe-antificrobial kunye nolawulo olujolise kulo.

Ukuhlelwa kosulelo lwegazi ngokuqatha ngokwenqanaba losulelo

IBacteraelia

Ubukho bebhacteria okanye ifungi kwigazi.

Septicemia

Isifo sekliniki esibangelwa kukuhlaselwa kwentsholongwane ye-pathogenic kunye neetyhefu zabo kwigazi, sisifo esinzima senkqubo.

Pyohemia

Ukungasongeli se-ADFFNTONS EYENZIWEYO NGOKUFANELEKILEYO NGOKUFANELEKILEYO UKUVULWA KWEEMPAHLA KWENKQUBO YOKUZIPHATHA.

Inkxalabo enkulu yeklinikhi yezi zosulelo ezimbini ezinxulumene nazo.

Usulelo lwegazi olukhethekileyo

Usulelo lwegazi olunxulumene ne-catheters ifakwe kwimithambo yegazi (umz. I-Cahesters ye-Peehester, i-Cahesters ye-Peetheras, i-Cahesters ye-venous ye-venous, i-catherial ye-cathers, i-casheters, njl.).

I-Endocitis ekhethekileyo

Sisifo esosulelayo esibangelwa kukufuduka kwee-pathogns kwi-endocium kunye nentliziyo ye-endocardium, kwaye iphawulwa ngokusekwa kwezinto eziphilayo eziveleni, kwaye yi-EneAstasis yosulelo okanye i-sepsis ngenxa yokutsalwa kwento engafunekiyo.

Iingozi zokusweleka kwegazi:

Usulelo lwegazi luchazwa njengesigulana esinenkcubeko efanelekileyo yegazi kunye neempawu zosulelo lwenkqubo. Usulelo lwegazi lunokuba sesibini kwezinye iisayithi zosulelo olunjengosulelo lwemiphunga, usulelo lwesisu, okanye usulelo oluyintloko. Kuxelwe ukuba i-40% yezigulana ene-seppis okanye i-septic yothuka ibangelwa lusulelo lwegazi [4]. Kuthelekelelwa ukuba amatyala angama-47-50 ee-sepsis yenzeka kwihlabathi liphela, obangela ukufana kwezigidi ezili-11, ngomndilili we-1 yemizuzwana emi-5].

Iindlela ezikhoyo zokuqonda isifo segazi

I-01 PCT

Xa usulelo olusebenzayo kunye nokuphendula kwe-inflamitory, ukugcinwa kwe-pickoninogenigen ye-CCT kunyusa ngokukhawuleza i-thexil toxins kunye nenqanaba le-cymmatory libonisa imeko enzulu yesi sifo kwaye sisiphawuli esihle se-prognosis.

I-0.2 iiseli kunye ne-adhesions

Iimolekyuli zeseli zeseli (Cam) zibandakanyeka kuthotho lweenkqubo zembonakalo zomzimba, ezinje ngempendulo yomzimba kunye nempendulo ye-inflayiti, kwaye zidlale indima ebalulekileyo kusulelo oluchasene nosulelo olunzulu kunye nosulelo olunzulu. Oku kubandakanya i-IL-6, il-8, i-TNF-A, VCCAM-1, njl.

I-Endotoxin ye-03 EndotoxIn, Vavanya

I-GRAM-ANGRINIA engalunganga efaka igazi lokukhupha i-endotoxin inokubangela i-endoksia; .

I-04 molecular biology

I-DNA okanye i-RNA ikhutshwe egazini zii-microorganisms ivavanywa, okanye emva kwenkcubeko efanelekileyo yegazi.

I-05 inkcubeko yegazi

Intsholongwane okanye ifungi kwiinkcubeko zegazi "ngumgangatho wegolide".

Inkcubeko yegazi yenye yezona ndlela zilula, zichanekile kwaye uninzi lwezinto ezisetyenzisiweyo zokufumana usulelo lwegazi kwaye sisiseko se-pathogenic sokuqinisekisa usulelo lwegazi emzimbeni. Ukufunyanwa kwangoko kwenkcubeko yegazi kwaye kwangethuba kunye nonyango olufanelekileyo kunye nonyango olululo ngamanyathelo aphambili ekufuneka athatyathwe ukulawula usulelo lwegazi.

Inkcubeko yegazi nguMgangatho weGold of sosulelo lwegazi, olunokuhlula ngokuchanileyo ukosulela i-pathogen, dibanisa ngokuchonga izicwangciso zemvakalelo yeziyobisi kwaye unike isicwangciso sonyango esichanekileyo. Nangona kunjalo, ingxaki yexesha elide yokunika ingxelo yenkcubeko yenkcubeko ichaphazele ukuxilongwa kweklinikhi kunye nonyango, kwaye kuxelwe ukuba izinga lezinga lokubhubha zingaphathwa ngamaxesha ama-7.6% ngeyure emva kweeyure ezi-6 zoxinzelelo lokuqala.

Ke ngoko, inkcubeko yangoku yegazi kunye nokuchongwa kweemvakalelo zegazi ezikrokrelweyo zisebenzisa inkqubo ye-IRier ekwanti, iNgxelo yeXesha eliNgcono (iNgxelo yeXesha Eliqhelekileyo (i-Alam Gqibezela i-Speention Times) [7]. Ingxelo ephambili kufuneka ixelwe kwikliniki ngaphakathi kwe-1 h yengxelo yegazi elungileyo yegazi; Ingxelo ye-Tearch kuyacetyiqeshwa ukuba igqitywe ngokukhawuleza (ngokubanzi ngaphakathi kwe-48-72 h ye-bacteria) kuxhomekeka kwimeko yelebhu.