Izigulana zomhlaza eziphunga, Ngaba uvavanyo lwe-MRD luyimfuneko?

I-MRD (isifo esincinci esincinci), okanye isifo esincinci esincinci, linani elincinci leeseli zomhlaza (iiseli zomhlaza ezingaphenduli okanye azichasanga kunyango) onyango emva konyango lomhlaza.
I-MRD inokusetyenziswa njenge-biomarker, ngesiphumo esihle seso izilonda eziyintsalela zisenokufunyanwa emva konyango oluza kubhatalwa, kwaye kuqalile ukuphinda-phinda isifo emva kokuba unyango lwentsalelo);
Kuyaziwa ukuba uvavanyo lwe-MRD ludlala indima ebalulekileyo ekuchongeni izigulana ezingaphambili zomhlaza weseli
Iimeko apho i-MRD ingasetyenziswa khona:

Ngomhlaza oSebenzayo oSebenziyo

1. Emva kokuphathwa kwenqanaba lokuqala leSungs Iseli, i-Mrd Pormatity ibonisa umngcipheko omkhulu wokuphinda uqalise kwaye ufuna ulawulo olusondeleyo olusondeleyo. Ukuhlolwa kweliso kwi-MD kuyacetyiswa qho kwiinyanga ezi-3-6;
2. Kucetyiswa ukuba wenze uvavanyo lwezonyango lwezonyango lweseli engekho mgangathweni isekwe kwi-MRD, kwaye ukubonelela ngeendlela ezifanelekileyo zonyango oluchanekileyo;
3. Cebisa ngokuphonononga indima ye-MRD kuzo zombini iintlobo zezigulana, umqhubi onento yokwenza novelwano, ngokwahlukeneyo.

I-ekuhlaleni i-wangs yesele incinci

I-1.mdd Ukuvavanywa kuyacetyiswa kwizigulana ekuxolweni ngokupheleleyo emva kokuxolelwa kwe-radical ye-chemoradiotheratical yeseli, enokunceda ekuqinisekisweni kwaye enze ezinye iindlela zonyango;
2. Izilingo zeklinikhi zonyango olusekwe kwi-MRD lokudibanisa emva kokuba i-chemoradiotherapy iyacetyiswa ukubonelela ngeendlela ezichanekileyo zonyango kangangoko kunokwenzeka.
I-piler yomhlaza weseli
1. Kukho ukunqongophala kwezifundo ezifanelekileyo kwi-MRD kwi-Advar ePrivel Wist;
2. Kucetyiswa ukuba i-MRD ifunyanwe kwizigulana ezilandelwa ngokupheleleyo emva konyango olungelulo lwe-ist Advar, olunokunceda ukugweba isifo se-prognosis kwaye sisebenzise ezinye iindlela zonyango;
3. Kucetyiswa ukuba wenze uphando malunga neendlela ezisekwe kwi-MDD kwizigulana ezixolweni ngokupheleleyo ukuze ziphinde zixolelwe ixesha lokuxolelwa ngokupheleleyo kangangoko kunokwenzeka ukuba izibonelelo zazo zinokukhulisa izibonelelo zabo.

Ingabonwa ukuba ngenxa yokunqongophala kwezifundo ezichaphazelekayo kwi-MRD yomhlaza we-LIGS
Kwiminyaka yakutshanje, inkqubela phambili ekugxilwe kuyo kunye nemmunotherapy ihambe iguqukele kwimbono yonyango yezigulana ezine-NSCLC ephezulu.
Ubungqina obuvelayo bubonisa ukuba ezinye izigulana ziphulukene nexesha elide kwaye zilindelwe ukuba zifezekise uxolelo olupheleleyo ngokwenza. Ke ngoko, phantsi kweso sithuba sokuba amanye amaqela abaguli ane-NSCLC ehamba ngokuthe ngcembe, kwaye ukuhlola izifo awazisile imbambano enkulu yeklinikhi, nokuba uvavanyo lwe-MRD lunokudlala indima ebalulekileyo kuyo ifanelwe kukuqhubeka nokuvavanywa.