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Kwicandelo leemviwo zebhayoloji yemolekyuli, izinto ezinje ngokusebenza kakuhle kwesithuba sezixhobo, ukwenziwa komsebenzi, kunye nokuthembeka kwedatha zichaphazela ngokuthe ngqo inkqubela yophando kunye nomgangatho weziphumo zesayensi. Ukujongana nemingeni eqhelekileyo yelabhoratri—ukusasazwa okulinganiselweyo ngenxa yeenyawo ezinkulu zezixhobo, ukusebenza okuphantsi ekucutshungulweni kweesampuli ngaxeshanye, kunye nokungaphindaphindeki kwedatha okuchaphazela ukuthembeka kweziphumo—I-BigFisure's FC-48D PCR Thermal Cycler esandula ukuqaliswa isebenzisa uyilo oluphambili lweenjini ezimbini kunye noyilo lwenkqubo olukrelekrele ukubonelela ngezisombululo ze-PCR ezichanekileyo nezisebenzayo kakhulu kwiilabhoratri zophando zaseyunivesithi, i-biopharmaceutical R&D, kunye novavanyo olungxamisekileyo lwempilo yoluntu.
I-FC-48D iphumelele kakhulu ekwenzeni ngcono indawo ngoyilo lwayo lomzimba oluncinci. Ngaphandle kokuphazamisa ukusebenza kwayo, inciphisa kakhulu unyawo lwesixhobo, ivumela ukubekwa okuguquguqukayo kwiibhentshi zelebhu eziqhelekileyo, kwiindawo zokusebenzela ezincinci ze-R&D, kwanezithuthi zovavanyo ezihambayo apho indawo incinci khona. Oku kusombulula ngempumelelo umba wexesha elide wee-PCR cyclers zemveli "ezinkulu kwaye kunzima ukuzibeka."
Kwangaxeshanye, esi sixhobo sineemodyuli ezimbini ezilawulwa ngokuzimeleyo ezinoqwalaselo lomthamo wesampulu ezingama-48×2, zifezekisa ngokwenene "umatshini omnye, usetyenziso oluphindwe kabini." Abasebenzisi banokusebenzisa iiprotokholi ezahlukeneyo ngaxeshanye (umz., ukwandiswa kwe-PCR rhoqo kunye nokuhlolwa kwe-primer specificity) okanye baqhube iiseti ezininzi zeesampulu ngaxeshanye. Oku kuphucula kakhulu i-throughput ngexesha ngalinye, kuthintela ukulibaziseka kophando okubangelwa kukufumaneka kwezixhobo okuncinci, kwaye kubonelela ngesiseko esiqinileyo sehardware sovavanyo olusebenzayo oluphezulu.
Ukusebenza koLawulo loBushushu oluPhuculweyo kunye namava oMsebenzisi
Itekhnoloji yoLawulo loBushushu obuPhambili
Eyona nto iphambili ekusebenzeni kwayo, i-FC-48D isebenzisa ubuchwepheshe bokulawula i-PID ye-thermoelectric semiconductor ye-BigFisure ukuze inikeze amazinga okufudumeza nokupholisa ngokukhawuleza kakhulu. Xa ithelekiswa nee-cyclers ze-thermal ze-PCR eziqhelekileyo, inciphisa ixesha lovavanyo ngaphezulu kwe-30%, nto leyo enciphisa uxinzelelo lwexesha kubaphandi abasebenza phantsi kweshedyuli yeprojekthi enzima.
Okubaluleke ngakumbi, nokuba isebenza ngesantya esiphezulu, inkqubo igcina ukuchaneka okugqwesileyo kobushushu kunye nokufana. Kwiqondo lobushushu elibalulekileyo le-55°C, ibhloko yobushushu iqinisekisa iimeko zobushushu ezihambelanayo kuzo zonke ii-wells ezingama-96 zenkqubo ye-dual-module, inciphisa ukuguquguquka okubangelwa bubushushu kwaye iqinisekisa ukuphindaphindwa okuphezulu kunye nokuthembeka kweziphumo.
Ukuxhasa ngakumbi imisebenzi enzima efana nokwenza ngcono i-primer kunye nokuhlolwa kwemeko yokusabela, i-FC-48D ibandakanya amandla okubonisa ubushushu obuthe nkqo obubanzi. Oku kuvumela abaphandi ukuba bavavanye iiparameter ezininzi zobushushu ngaphakathi kwexesha elinye—ukususa imijikelo yovavanyo oluphindaphindwayo kunye neempazamo kwaye kuncitshiswe kakhulu umthwalo wokusebenza kwezilingo ezinzima.
Ukusebenziseka lula kunye noKhuseleko lovavanyo
Ukulinganisela ukusebenza kobungcali kunye noyilo olulula ukuyisebenzisa, i-FC-48D ibandakanya:
- Isikrini sokuchukumisa esinombala esiyi-intshi ezi-7 esivumela ukusetwa kwenkqubo ngendlela eqondakalayo, ukulungiswa kweparameter, kunye nokubeka esweni ngexesha langempela
- Umboniso wesimo sempendulo yemizobo yexesha langempela ukuze kubonakale ngokupheleleyo ngexesha lovavanyo
- Ukumisa ngokuzenzekelayo kunye nokukhuselwa kokulahleka kombane, ukukhusela iisampulu ngexesha lokuphazamiseka kombane okanye iimpazamo zenkqubo
- Isiciko esishushu esikrelekrele esizilungisa ngokuzenzekelayo ukukhusela iisampuli, ukugcina uzinzo lwemveliso, kunye nokuxhasa ukusebenza kakuhle kwamandla
Izicelo Ezininzi Kwiinkalo Zophando
Njengesixhobo esisebenza kakuhle esenzelwe ukusetyenziswa kwiindawo ezininzi, i-FC-48D ixhasa uluhlu olubanzi lwezicelo, kuquka:
- Ukwandiswa kwe-nucleic acid esisiseko
- Ukwandiswa kokuthembeka okuphezulu
- ukwenziwa kwe-cDNA
- Ukulungiselela ithala leencwadi
- Kunye neminye imisebenzi eyahlukeneyo enxulumene ne-PCR
Yenzelwe ukuhlangabezana neemfuno ezahlukeneyo nezitshintshayo zeeprojekthi ezahlukeneyo zophando lwesayensi.
Ukuba ungathanda ukufumana i-datasheet yobugcisa eneenkcukacha, ucele iyunithi yokubonisa, okanye uthethe ngokuthenga, nceda unxibelelane neqela lethu usebenzisa inombolo yefowuni engezantsi.
Vumela i-FC-48D ibe yi-accelerator yakho ukuze uphando lusebenze kakuhle!
Ixesha lokuthumela: Disemba-11-2025
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