Indima ebalulekileyo ye-iNuleic Acid kwi-biotechnology ye-biotechnology

Kwindawo ekhula ngokukhawuleza ye-biotechnology, ukukhutshwa kwee-acids ze-nucleic (i-DNA kunye ne-RNA) iye yaba yinkqubo esisiseko yezicelo ukusuka kuphando lwendalo. Kwintliziyo yale nkqubo yi-nucleid ye-activa, isixhobo esibalulekileyo esikhanyisa i-BOIBRA YOKUZIPHATHA NGOKUGQIBELA KWIINQAKU ZOBUGCISA. Kwezi bhlog, siza kuphonononga ukubaluleka kwe-intecractor, indlela abasebenza ngayo, kunye nefuthe lazo kuphando lwezenzululwazi kunye nokuhambela phambili kwezonyango.

Ukuqonda i-acid acids

I-nucleic acids yibhloko yobomi, ethwele ulwazi lwemfuzo olufunekayo ekukhuleni, uphuhliso kunye nomsebenzi wazo zonke izinto eziphilayo. I-DNA (Deoxyribonucleic Acid) yi-Blobrint yelifa lemfuza, ngelixa i-RNA (i-ribonuccic acid) idlala indima ebalulekileyo ekutyibilini iinkcukacha zofuzo. Ukukwazi ukukhupha nokuhlalutya ezi zifundo ze-nucleic kubalulekile kwizifundo ezininzi zesayensi ezinjengee-ekudeni, ii-transcriptomics kunye nengcinezelo yemolekyuli.

Ukubaluleka kokukhutshwa kwe-nucleic

Ukukhupha i-nucleic straction linyathelo elibalulekileyo kwiinkqubo ezininzi zelebhu. Nokuba isetyenziselwa ukucamngca, ukulandelelana okanye umgangatho wokufakelwa, umgangatho kunye nokucoceka kwee-asidi zenyukliya ezikhutshiweyo kunokuchaphazela kakhulu iziphumo zovavanyo. Iindlela zokukhupha zemveli, ezinjenge-phelelol-chloroforn yokukhutshwa, inokusebenza kakhulu kwaye ichitha ixesha elide kwaye ichitha ixesha, kwaye idla ngokukhokelela kwiziphumo ezingahambelaniyo. Kulapho izixhobo ze-nucleid zenyukliya zinokudlala.

UMGAQO-NKQUBO WOKUSETYENZISWA KOKUSETYENZISWA KOMSEBENZI

I-Nuleic Acid I-Acid I-Acid I-Acid I-Acid I-Acid I-AICTRATOTORSSebenzisa iindlela ezahlukeneyo zobuchwephesha ukwahlula iDNA kunye ne-RNA kwiiseli kunye nezicubu. Uninzi lwabasebenzi bale mihla basebenzisa iinkqubo ezenzekelayo ezidibanisa amanyathelo amaninzi inkqubo yokukhuphela, kubandakanya iseli yeylisi, ukucocwa kunye nesisongelo. Ezi nkqubo ziqhele ukusebenzisa iikholamu ezisekwe kwi-silica-ze-asicic okanye iibhloti zemagnetic ukuze zibopheleleke i-acid acids, ngaloo ndlela zisusa ungcoliseko olunje ngeeproteni kunye nee-lipids.

I-Automaiction ye-Incleic Shortsuction ayiphuli kuphela ukusebenza ngaphandle kokusebenza kwempazamo yomntu, imphumo kwiziphumo ezingaguqukiyo nezibuyisiweyo. Ukongeza, izixhobo ezininzi zokukhuphela i-acid zenzelwe ukuqhubela phambili iisampulu ezininzi ngaxeshanye, zibenzela ukuba zilungele ukuqalisa izinto ezingena kuphando kuphando kunye noseto lwekliniki.

Uphando kunye nezicelo zonyango

Izicelo ze-nucleid acid intsebenzo ebanzi kwaye yahluka. Kwiilebhu zophando, izixhobo ze-nucleic acid ziyizixhobo ezinokubakho kwi-NEIMOPE yoPhando, zisebenze izazinzulu zokuhlalutya ukwahluka kwendalo, kunye nokuphonononga ubudlelwane bendalo. Kwiseto sekliniki, ukuthotyelwa kwe-nucleic straction kubalulekile ekuchongeni izifo ezosulelayo, izifo zemfuza kunye nomhlaza. Ukukwazi ukukhawuleza nangokuchanekileyo kukhupha ngokuchanekileyo i-acid yenyukliya kwiisampulu zesigulana ivumela izigqibo zonyango ngexesha elifanelekileyo nezisebenzayo.

Ukongeza, ukunyuka kweyeza ezenziwa ngobuntu kuye kwabona ukubaluleka kokukhuphela i-nucleic acid. Njengabachwephesha abajolise kuzo ngakumbi balungelelaniswe kwi-feetrol yemfuza yomntu ophumayo, imfuno yee-apid ezisemgangathweni ezisemgangathweni ziya kuqhubeka zikhula.

ukuququmbela

Isishwankathelo,I-Nuleic Acid I-Acid I-Acid I-Acid I-Acid I-Acid I-AICTRATOTORSzizinto eziyimfuneko kwicandelo le-biotechnology, encedisa ekukhuthazeni ngokufanelekileyo kwaye ngokuthembekileyo i-DNA kunye ne-RNA kwiisampulu ezahlukeneyo. Impembelelo yabo kuPhando kunye neKlinikhi yeKlinikhi ayinakuba ngaphezulu, njengoko zenza ukuba oososayensi kunye neengcali zempilo ukuvula iimfihlo ze-genome kwaye ziphucule iziphumo zoonesi. Njengoko itekhnoloji iyaqhubeka ukuqhubela phambili, sinokulindela ukuba i-nucleid aciccers iqhubeke nokuvela, ukuphucula amandla abo kunye nokusetyenziswa kweSayensi yoBomi. Enoba ungumphandi, ugqirha wezonyango, okanye inkxalabo yesayensi, ukuqonda indima ye-nucleic acid iphambili ekuqinisekiseni inkqubela phambili emangalisayo eyenziwe kwicandelo le-biotechnology.