Iindaba zeVeteriene: Inkqubela phambili kuPhando lwe-Avian Fool

Iindaba 01

Ukufunyanwa kokuqala kwe-H4N6 ye-H4N6 yeVidiyo ye-Avian Fools kwi-Mallard Dacks (Anas Platyrhynchos) kwaSirayeli

Avishai lublin, nikki tie, irina skoda, gila kahali, riurine l qamati, rauri thetz, rauri cek, uNathan

I-PMID: 35687561; DOI: 10.1111 / tdibe.14610

Intsholongwane ye-Avian Influenzanza (AIV) ibeka isoyikiso esikhulu kwi-Aguds nakwimpilo yabantu. Njengoko i-Wildfowl idluliselwe kwi-AIV ehlabathini lonke, phanda ukwanda kwe-AIV kwizilwanyana zasendle kubalulekile ekuqondeni ukosulelwa kwe-pathogen kwizilwanyana zasekhaya nakwizilwanyana. Kolu phononongo, i-H4N6 I-AIV ye-AIV i-Aiv idityanisiwe okokuqala ukusuka kwiisampulu ze-factal amadada eluhlaza (Anas Platyrhynchos) kwaSirayeli. Iziphumo ze-phylogenetic ze-ha kunye ne-nan ibonisa ukuba le ngxaki inxulumene ngokusondeleyo ne-European naseAsia yaseAsia. Njengoko u-Israel ebekwe kwi-Arctic-Arctic ye-Arctic-African indlela, kuthathwa ukuba uxinzelelo mhlawumbi lwazise iintaka ezifudukayo. Uhlalutyo lwe-phylogenetice Le sub6 ye-H4N6 ye-AIV inezinga eliphezulu, linokuvelisa iihagu ezisempilweni kwaye zibophelele iimvume zabantu, kwaye zinokubangela isifo sikaZoonotic kwixesha elizayo.

Iindaba 02

Amagqabantshintshi nge-Avian Fornuenza kwi-EU, nge-Matshi-Juni 2022

I-European Khuseleko loKhuseleko loKutya, iZiko laseYurophu kwizifo zoThintelo kunye noLawulo, iLabho le-Icalati yaseYurophu ye-Avian Influenza

I-PMID: 35949938; i-PMCID: PMC9356771; DOI: 10.7402022.7415

Ngo-2021 ukuya ku -02, i-Avic ye-Avian ye-Avian ye-Avian Phakathi kwe-16 Matshi 2022, i-28 ye-28 ye-EU / ye-EEEA kunye ne-UK 1 182 imingxunya ye-UK 1 182 ye-In Cansins ye-Avian Foos (i-HPAIV), amatyala angama-410) kunye neentaka ezi-410). Ngexesha lokuphononongwa, iipesenti ezingama-86 zokudluliselwa kwenkukhu kwakufanele ukuhambisa i-HPAIV, kunye ne-Accounting ye-Prance ye-68% ye-roughts robsry, iHungary i-24% kunye namanye amazwe achaphazelekayo angaphantsi kwe-2% inye. IJamani yayinelona nani liphezulu lokuqhuma kwiintaka zasendle (amatyala ali-158), kulandelwe yi-Netherlands (amatyala angama-98) kunye ne-UK (ama-48).

Iziphumo zohlalutyo lwemfuza zibonisa ukuba i-hpav okwangoku i-Europes ye-Europer'3.4 b. Kuba ingxelo yokugqibela, i-H5N6 ye-H5N2, i-H9N2 kunye nezifo ze-H33n8 zichaziwe eTshayina kunye nosulelo olunye lwe-H5N1 ziye zaxelwa e-USA. Umngcipheko wokosuleleka uvavanywe njengeziphantsi zabantu ngokubanzi kwaye uphantsi kokumodareyitha abantu abachaphazelekayo kwi-EU / EEA.

 Iindaba 03

Ukuguquguquka kwintsalela i-127, 183 kunye ne-212 kwi-hage ichaphazela

Ukuhlazeka, ukuphindaphinda kunye ne-pathoanity ye-H9N2 intsholongwane ye-Avian

I-Menglu fan,I-Bing Liang,Yongzzhen Zhao,I-Yapling Zhang,Qngzheng liu,Miao tian,I-YIQng Zheng,Huizhi xia,Yasuo suzuki,Hualan chen,Jihui ping

I-PMID: 34724348; DOI: 10.1111 / i-tbed.14363

Intsholongwane ye-H9N2 yeVidiyo ye-H9N2 ye-Avian Ensuenzanza (AIV) yenye yezona zinto zityhutywe ezichaphazela impilo yeshishini lenkukhu. Kolu phononongo, uninzi lweengxaki ezimbini ze-H9N2 I-AIV efanayo yemfuza yemfuza yemfuza kodwa egama lingu-A / inkukhu / i-jiangsu / 76 / i-jiangsu / 76), yahlukaniswa kwifama yenkukhu. Uhlalutyo loLululeko lubonise ukuba i-JS / 75 ne-JS / 76 eyahlukileyo kwintsalela ezintathu ze-Amino Alid (127, 183 nangama-212) ye-hamagglutinin (ha). Ukuphonononga umahluko kwiipropathi zebhayoloji phakathi kwe-JS / 75 ne-JS / 76, iintsholongwane ezintandathu eziphindaphindwayo zivelisiwe kusetyenziswa i-genege yemfuza esebenzisa i-A / Puerto Rico / i-PR8) njengekhonkco eliphambili. Idatha evela kuvavanyo lwenkukhu kunye neemvavanyo ze-HI zibonisa ukuba i-R-76 / pr8 ibonakaliswe kakhulu ukubaleka ngenxa yotshintsho lwe-Amino Acid kwizikhundla ezili-127 kunye no-183 kwi-gene. Izifundo ezizezinye ziqinisekisile ukuba i-Glycosysing kwindawo ye-127n yenzekile kwi-JS / 76 kunye nokuguquka kwayo. I-Readpptor Ukubopha i-Assays kubonise ukuba zonke iintsholongwane eziqinisekileyo, ngaphandle kwe-127n ye-127 ye-gelycossition ye-gelycosysicy, iboshwe ngokulula kwii-remanoretors. Ukukhula kwe-Kinetics kwi-Kinetics Kinetics kunye nokuhlasela kwemouse kubonise ukuba intsholongwane ye-127n-gelycosty ephindaphindwayo iphinde iphinda iphindwe kancinane kwiiseli ze-A549 kwaye yayingaphantsi kwe-pathogenic kwi-vis yohlobo lwasendle. Ngenxa yoko, i-Glycosysition kunye ne-Amino Acid yotshintsho kwi-hage inoxanduva lolwahluko kwi-antignicity kunye ne-pathogenity ye-2 h9n yoxinzelelo.

Umthombo: IZiko leMpilo yeZilwanyana zasePina kunye neZiko leSikolo