Ukukhawulezisa ukuxilongwa kwezifo ezithembekileyo

Ukuxilongwa kulibaziseka kwizifo ezosulelayo ibeka abantu abaninzi emngciphekweni kwihlabathi lethu lehlabathi, ngakumbi ngezifo ze-zoonotic ezisasazwa phakathi kwezilwanyana kunye nabantu. Kuqikelelwa ukuba i-75% ye-30 ye-pathogens esandula ukuchongwa ebhalwe kwiminyaka engama-30 edlulileyo ngo-2008 imvelaphi yezilwanyana, ngokwengxelo ye-WHO ekhutshwe ngo-2021.

"Iqela lethu lizinikele ekoyiseni imingeni yoyilo lokuxilonga ukuze isebenze isidingo sokuxilonga isantya se-POCT kunye nokufikeleleka kuzo zombini i-IVD (i-In vitro) kunye ne-IVD engekho, "kusho uLianyi Xie, owasungula i-Hangzhou Bigfish Bio-tech Co., Ltd, kwi-2017. "Iimvavanyo zethu zokunyamekela (i-POCT) zenzelwe ukusebenza ngokukhawuleza kwiimeko ezinobuncwane, ngelixa i-catering. kwizifo ezahlukahlukeneyo.”

Ii-POCT zeBigfish zenzelwe ukukhusela ukhuseleko lokutya, kunye nempilo yemfuyo kunye nezilwanyana ezingamaqabane, ngakumbi kuthathelwa ingqalelo inani elandayo laseTshayina labanini bezilwanyana zasekhaya.

Ukwamkelwa kwe-POCT ngokukhawuleza, u-Xie wachaza, kufuneka anyathele ibhalansi elungileyo phakathi kwezinto ezintsha kunye nokugxila kwi-teknoloji yendabuko kunye nethembekileyo yokukhulisa iteknoloji, esekelwe kwi-polymerase chain reaction (PCR), ukufumanisa ubuninzi bemizuzu ye-nucleic acids kwimidiya enzima.

Cinga ngokuqhambuka kwe-African swine fever (ASF) e-China, ikhaya leyona mveliso inkulu yehlabathi yehagu kunye nentengiso esetyenziswayo. Ngo-2019, i-ASF yabangela ukufa kweehagu ezingaphezulu kwezigidi ezingama-43, kwaye malunga ne-111 yeebhiliyoni zeedola zaseMelika kwilahleko. Ukukhawulezisa uyilo lwe-POCT kuxhomekeke kwintsebenziswano esondeleyo nezifundiswa kunye namaqumrhu karhulumente, kunye nengxelo evela kubasebenzisi, abafana nabafuyi abakhulu beehagu base China.

"Ukuchaneka kunye novelwano ngokuhambelana nezicwangciso zelabhoratri, nakwiifama ezincinci ezikude, zibalulekile kwiikiti zethu, ezenziwe ukuba zifikeleleke kwaye zisebenziseke ngokulula nakuwuphi na umhlambi weehagu," kuchaza uXie.

Umsebenzi weBigfish ekuthinteleni nasekupheliseni izifo kwilizwe liphela udlulela nakwi-brucellosis, ehlala isesona sifo sixhaphakileyo kwihlabathi jikelele, kunye nezifo kwizilwanyana ezingamaqabane.

I-Bigfish iququzelele ngokukhawuleza i-POCT kumaziko onyango lwezilwanyana angama-4,000 kulo lonke elase-China. UShuilin Zhu, usihlalo weZhejiang Small Animal Protection Association, wongeze ukuba itekhnoloji yenkampani yezilwanyana.

ukufuywa kunye nokhathalelo lwezilwanyana zasekhaya akwanelanga nje ukwandisa ukusebenza kakuhle kokuthintela kunye nokulawula, kodwa kwakhona ukuphucula kakhulu intlalontle yezilwanyana.

Ukuvumela uyilo oludityanisiweyo ngaphandle kweendleko ezinkulu kubasebenzisi ngomnye umba ophambili kuyilo kunye nokwenziwa kovavanyo lwabo lwemfuza. Uvavanyo lwabo lwemolekyuli yokuxilonga i-GeNext ayikho nkulu kunebhotile yamanzi, kwaye inobunzima obuziikhilogram ezi-2. Ibonisa iitshiphusi ze-mesofluidic kunye ne-microfluidic ezenza ngokuzenzekelayo amanyathelo anzima ukusuka kwi-nucleic acid extraction, ulwandiso lofuzo ukuya kwi-real-time data upload kunye nohlalutyo.

Ivalwe ngokupheleleyo ukuthintela ukungcoliseka kwe-aerosol enokubakho, i-GeNext 2.0 ngoku kwimveliso yobuninzi inokwenza i-sampulu ikhule ukusuka kwi-1 ukuya kwi-16 ngomjikelo ngamnye, ulandelelwano olujoliswe kuyo lwandisiwe ukusuka kwi-5 ukuya kwi-25 ngokubaleka, ngaphandle kwexesha elongezelelweyo okanye iindleko.

Uyilo lwethu lwe-GeNext 3.0 luya kunciphisa ngakumbi ixesha, luphucule ngeetshiphusi ezise-silicon, kwaye lubandakanye itekhnoloji yokulandelelana efana nolandelelwano lwe-nanopore kumxholo obanzi wekliniki kuvavanyo lokubeleka kunye nokufunyaniswa komhlaza kwangoko, utshilo u-Xie. "Uyilo lwethu lwePOCT lunokuthi ngenye imini lusetyenziswe nguye nabani na, naphi na ngaphandle kokujonga iindleko."