Ukukhawulezisa ukuxilongwa kwezifo okunokuthenjwa

Ukuchongwa kwezifo ezithathelwanayo ngexesha elilibazisekileyo kubeka uluntu olusasazekileyo emngciphekweni kwihlabathi lethu elijikelezileyo, ingakumbi xa iintsholongwane zezilwanyana zisasazeka phakathi kwezilwanyana nabantu. Kuqikelelwa ukuba i-75% yeentsholongwane zabantu ezingama-30 ezisandula ukubonwa ezibhalwe kwiminyaka engama-30 edlulileyo ngo-2008 zivela kwizilwanyana, ngokutsho kwengxelo ye-WHO ekhutshwe ngo-2021.

"Iqela lethu lizinikele ekoyiseni imingeni yoyilo lokuxilonga ukuze kuhlangatyezwane nesidingo sokuxilonga sesantya se-POCT kunye nokufikeleleka kuzo zombini i-IVD (i-In vitro) kunye ne-non-IVD,” utshilo uLianyi Xie, owaseka iHangzhou Bigfish Bio-tech Co., Ltd, ngo-2017. “Uvavanyo lwethu lwe-point-of-care (POCT) lwenzelwe ukusebenza ngokukhawuleza kwiimeko ezinqongopheleyo, ngelixa lubonelela ngeentlobo ngeentlobo zezifo.”

Ii-POCT zeBigfish zenzelwe ukukhusela ukhuseleko lokutya, kunye nempilo yemfuyo kunye nezilwanyana ezihamba nazo, ingakumbi xa kujongwa inani elikhulayo labanini bezilwanyana zasekhaya eTshayina.

UXie ucacisile ukuba ukuvunywa koyilo lwePOCT ngokukhawuleza kufuneka kuhambelane kakuhle phakathi kobuchule bokuvelisa izinto ezintsha kunye nokugxila kubuchwepheshe be-amplification bendabuko nobuthembekileyo, obusekelwe kwi-polymerase chain reaction (PCR), ukuze kufunyanwe ubungakanani obuncinci be-nucleic acids kwi-complex media.

Cinga ngokuqhambuka kwe-African swine fever (ASF) eTshayina, ikhaya lemarike enkulu yemveliso yehagu kunye nokusetyenziswa kwayo emhlabeni. Ngo-2019, i-ASF yabangela ukufa kweehagu ezingaphezu kwezigidi ezingama-43, kwaye yabangela ilahleko emalunga ne-$US 111 yezigidigidi. Ukucwangcisa ii-POCT ngokukhawulezisa kuxhomekeke kwintsebenziswano esondeleyo neengcali zemfundo kunye norhulumente, kunye nengxelo evela kubasebenzisi, njengabafuyi beehagu abaphambili baseTshayina.

“Ukuchaneka kunye nokuqonda okulinganayo neendawo zelebhu, nokuba kumafama amancinci akude, kubalulekile kwiikiti zethu, ezenziwe zifikeleleke kwaye kulula ukuzisebenzisa kuyo nayiphi na ihagu,” ucacisa uXie.

Umsebenzi weBigfish wokuthintela nokuphelisa izifo kuzwelonke ukwafikelela nakwi-brucellosis, esisifo esihlala sixhaphakile kwihlabathi liphela, kunye nezifo kwizilwanyana ezihamba nazo.

IBigfish ikhawulezise i-POCT kwiindawo zezilwanyana ezimalunga nama-4,000 kulo lonke elaseTshayina. UShuilin Zhu, usihlalo weZhejiang Small Animal Protection Association, wongeze ngelithi ubuchwepheshe benkampani kwizilwanyana

Ukunyamekela izilwanyana zasekhaya kunye nokufuya akupheleli nje ekunyuseni ukusebenza kakuhle kokuthintela nokulawula, kodwa kukwaphucula kakhulu impilo-ntle yezilwanyana.

Ukuvumela uyilo oluncinci ngaphandle kweendleko ezinkulu kubasebenzisi yenye into ephambili kuyilo nakwimveliso yovavanyo lwabo lwemfuza. Uvavanyo lwabo lwe-molecular diagnostic GeNext alukho ngaphezu kwebhotile yamanzi, kwaye lunobunzima obuziikhilogram ezi-2. Lune-mesofluidic kunye ne-microfluidic chips ezizenzela ngokuzenzekelayo amanyathelo anzima ukusuka ekutsalweni kwe-nucleic acid, ukwandiswa kwe-gene ukuya ekufakweni kwedatha ngexesha langempela kunye nohlalutyo.

Ivalwe ngokupheleleyo ukuze kuthintelwe ungcoliseko olunokubakho lwe-aerosol, iGeNext 2.0 ngoku evelisa ngobuninzi inokwenza ukuba isampuli iphume ukusuka kwi-1 ukuya kwi-16 ngomjikelo ngamnye, ulandelelwano olujoliswe kulo lwandiswe ukusuka kwi-5 ukuya kwi-25 ngomjikelo ngamnye, ngaphandle kwexesha okanye iindleko ezongezelelweyo.

“Uyilo lwethu lweGeNext 3.0 luya kunciphisa ixesha ngakumbi, luphucule ngeetships ezisekelwe kwisilicon, kwaye lufake ubuchwepheshe bokulandelelanisa okufana nokulandelelanisa kwe-nanopore kwimeko ebanzi yeklinikhi kuvavanyo lokukhulelwa kunye nokuxilongwa komhlaza kwangoko,” utshilo uXie. “Uyilo lwethu lwePOCT lunokusetyenziswa nangubani na ngenye imini, naphi na ngaphandle kokuqwalasela iindleko.”